Meaningful Relief with Flurbiprofen 8.75 mg Spray in Patients with Sore Throat Due to Upper Respiratory Tract Infection

This paper presents the result from a randomised, double-blind study in adults with sore throat due to upper respiratory tract infection who took flurbiprofen (n = 249) or placebo spray (n = 256). Pain relief was assessed using the Sore Throat Relief Rating Scale.  In this study, flurbiprofen spray provided significantly greater relief versus placebo…

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Efficacy of the Adjuvanted Recombinant Zoster Vaccine (RZV) by Sex, Geographic Region, and Geographic Ancestry/Ethnicity: A Post-Hoc Analysis of the ZOE-50 and ZOE-70 Randomised Trials

Herpes zoster (HZ) risk appears to vary by sex and geographic ancestry/ethnicity. In 2 randomised clinical trials, participants received 2 doses of adjuvanted recombinant zoster vaccine (RZV) or placebo intramuscularly, 2 months apart. In this post-hoc analysis, the efficacy of RZV against HZ and postherpetic neuralgia (PHN) were investigated by sex, geographic region, and geographic…

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