Efficacy of the Adjuvanted Recombinant Zoster Vaccine (RZV) by Sex, Geographic Region, and Geographic Ancestry/Ethnicity: A Post-Hoc Analysis of the ZOE-50 and ZOE-70 Randomised Trials

Herpes zoster (HZ) risk appears to vary by sex and geographic ancestry/ethnicity. In 2 randomised clinical trials, participants received 2 doses of adjuvanted recombinant zoster vaccine (RZV) or placebo intramuscularly, 2 months apart. In this post-hoc analysis, the efficacy of RZV against HZ and postherpetic neuralgia (PHN) were investigated by sex, geographic region, and geographic…

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Locally Delivered Flurbiprofen 8.75 mg for Treatment and Prevention of Sore Throat: A Narrative Review of Clinical Studies

Antibiotics are inappropriately prescribed to many people with sore throat. As most cases of sore throat are viral and/or self-limiting, guidelines recommend symptomatic management as first-line treatment. This paper reviews the available clinical evidence for the efficacy and safety of low dose (8.75 mg) flurbiprofen, locally delivered to the throat for the symptomatic management of…

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